Speaker: Bruce Cuthbert, USA

Research Domain Criteria (RDoC): Toward a New Classification Framework for Research on Mental Disorders

Conservation Challenges to Preventing Primate Extinction

Bruce Rothschild1* and Virginia L. Naples2 1Department of Medicine, Northeast Ohio Medical University, Rootstown, OH 44272, USA and Carnegie Museum, Pittsburgh, PA 15273, USA 2Departmentof Biological Sciences, Northern Illinois University, DeKalb, IL 60115, USA *Corresponding author: Bruce Rothschild, Northeast Ohio Medical University, Rootstown, Carnegie Museum, Pittsburgh, PA 15213, USA, Tel:...

AWARD NUMBER: W81XWH-13-1-0354 TITLE: “Targeting the Adipocyte-Tumor Cell Interaction in Prostate Cancer Treatment” PRINCIPAL INVESTIGATOR:

s and presentations: “Nutrient sensing and Cancer Metabolism by the p62 autophagy pathway” University of Pennsylvania, Philadelphia, 2014. Speaker (Moscat). “New role of metabolic reprograming in stroma-induced tumorigenesis” Centre for Genome Regulation, Barcelona, Spain, 2014. Speaker (Moscat). “Metabolic Reprogramming by the p62 Pathway in Cancer” in the “2014 ASIP Annual Meeting at Experime...

Novel Role for Pendrin in Orchestrating Bicarbonate Secretion in Cftr-expressing Airway Serous Cells

NOVEL ROLE FOR PENDRIN IN ORCHESTRATING BICARBONATE SECRETION IN CFTR-EXPRESSING AIRWAY SEROUS CELLS James P Garnett, Emma Hickman, Rachel Burrows, Péter Hegyi, László Tiszlavicz, Alan W Cuthbert, Peying Fong and Michael A Gray Institute for Cell & Molecular Biosciences, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.; Novartis Institutes for Biomedical Research (NIBR), Novartis Horsham...

Human Immune System Development and Rejection of Human Islet Allografts in Spontaneously Diabetic NOD-Rag1 IL2r null Ins2 Mice

RESEARCH DESIGN AND METHODS—We backcrossed the Ins2 mutation onto the NOD-Rag1 IL2r null strain and determined 1) the spontaneous development of hyperglycemia, 2) the ability of human islets, mouse islets, and dissociated mouse islet cells to restore euglycemia, 3) the generation of a human immune system following engraftment of human hematopoietic stem cells, and 4) the ability of the humanize...